Search results for "Enzyme biosynthesis"

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Effects of Indole-3-Carbinol and Flavonoids Administered Separately and in Combination on Nitric Oxide Production and iNOS Expression in Rats

2010

Beneficial effects of natural compounds are often attributed to modulation of NO production; however effects produced by plant extracts do not correlate with effects of purified components. The goal of our work was to study ability of flavonoids and indole-3-carbinol, as well as their combinations to modify NO production, iNOS gene and protein expression in rat tissues. Baicalein and luteolin decreased NO concentration in both intact and LPS-treated animals. Baicalein decreased iNOS gene expression. Luteolin decreased NO production in the liver and heart and number of iNOS-positive cells in the liver of LPS-treated animals. Combination of the two substances did not decrease the NO synthesis…

Enzyme biosynthesisSpleenGeneral MedicineGeneral ChemistryPharmacologyBiologyNitric oxideBaicaleinchemistry.chemical_compoundmedicine.anatomical_structurechemistryBiochemistryGene expressionmedicineIndole-3-carbinolQuercetinLuteolinChinese Medicine

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